investigation the efficacy of intra-articular prolotherapy with erythropoietin and dextrose and intra-articular pulsed radiofrequency on pain level reduction and range of motion improvement in primary osteoarthritis of knee
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چکیده
normal 0 false false false en-us x-none fa background: osteoarthritis is one of the most common diseases and the knee is the most commonly affected joint. intra-articular prolotherapy is being utilized in acute and chronic pain management setting. this study was designed to compare the efficacy of three methods of intra-articular knee joint therapies with erythropoietin, dextrose, and pulsed radiofrequency. materials and methods: after approval by the ethics committee and explaining the therapeutic method to volunteers, 70 patients who were suffering from primary knee osteoarthrosis went through one of the treatment methods (erythropoietin, dextrose, and pulsed radiofrequency). the study was double-blind randomized clinical trial performed from december 2012 to july 2013. patients’ pain level was assessed through the visual analog pain scale (vas), and range of motion (rom) was measured by goniometric method. furthermore, patients’ satisfaction was assessed before and after different treatment methods in weeks 2, 4, and 12. for analysis, chi-square, one-way anova, and repeated measured anova were utilized. results: the demographic results among the three groups did not indicate any statistical difference. the mean vas in erythropoietin group in the 2 nd , 4 th , and 12 th weeks was 3.15 ± 1.08, 3.15 ± 1.08, and 3.5 ± 1.23, respectively (p ? 0.005). knee joint rom in the erythropoietin group in the 2 nd , 4 th , and 12 th weeks was 124 ± 1.50, 124 ± 1.4, and123 ± 1.53 respectively (p ? 0.005). satisfaction score in the 12 th week in erythropoietin group was extremely satisfied 15%, satisfied 55%, and moderately satisfied 30%, (p = 0.005). no specific side-effects were observed. conclusion: intra-articular prolotherapy with erythropoietin was more effective in terms of pain level reduction and rom improvement compared with dextrose and pulsed radiofrequency.
منابع مشابه
Investigation the efficacy of intra-articular prolotherapy with erythropoietin and dextrose and intra-articular pulsed radiofrequency on pain level reduction and range of motion improvement in primary osteoarthritis of knee
BACKGROUND Osteoarthritis is one of the most common diseases and the knee is the most commonly affected joint. Intra-articular prolotherapy is being utilized in acute and chronic pain management setting. This study was designed to compare the efficacy of three methods of intra-articular knee joint therapies with erythropoietin, dextrose, and pulsed radiofrequency. MATERIALS AND METHODS After ...
متن کاملPeriarticular dextrose prolotherapy instead of intra-articular injection for pain and functional improvement in knee osteoarthritis
BACKGROUND Osteoarthritis (OA) is a degenerative disease that can lead to painful and dysfunctional joints. Prolotherapy involves using injections to produce functional restoration of the soft tissues of the joint. Intra-articular injections are controversial because of the introduction of needles into the articular capsule. OBJECTIVES To compare the effect of periarticular versus intra-artic...
متن کاملChondrogenic Effect of Intra-articular Hypertonic-Dextrose (Prolotherapy) in Severe Knee Osteoarthritis.
BACKGROUND Dextrose injection is reported to improve knee osteoarthritis (KOA)-related clinical outcomes, but its effect on articular cartilage is unknown. A chondrogenic effect of dextrose injection has been proposed. OBJECTIVE To assess biological and clinical effects of intra-articular hypertonic dextrose injections (prolotherapy) in painful KOA. DESIGN Case series with blinded arthrosco...
متن کاملThe Treatment of Joint Pain with Intra-articular Pulsed Radiofrequency
BACKGROUND The intra-articular (IA) application of pulsed radiofrequency (PRF) for pain in small and large joints represents a recent development that has proven to be effective in many cases. We performed a retrospective study of 89 such procedures in 57 consecutive patients with chronic articular pain. OBJECTIVES The aim of this retrospective study is to evaluate the effectiveness of intraa...
متن کاملComparative effectiveness of intra-articular prolotherapy versus peri-articular prolotherapy on pain reduction and improving function in patients with knee osteoarthritis: A randomized clinical trial
Background Osteoarthritis is a common degenerative disease. Prolotherapy is an alternative therapy used in multiple musculoskeletal disorders. Objective To compare the effectiveness of intra-articular dextrose injection versus peri-articular prolotherapy in patients with knee osteoarthritis (KOA). Methods Fifty-two adults with painful primary knee osteoarthritis for at least three months we...
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عنوان ژورنال:
journal of research in medical sciencesجلد ۱۹، شماره ۸، صفحات ۰-۰
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